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Pan-Cancer Analysis Uncovers Structural Variants as Vital Contributors to Tumor Neoantigens | # tumor genome

Pan-Cancer Analysis Uncovers Structural Variants as Vital Contributors to Tumor Neoantigens

Pan-Cancer Analysis Uncovers Structural Variants as Vital Contributors to Tumor Neoantigens

Although current investigations into neoantigens have predominantly concentrated on single nucleotide variants (SNVs) and insertion/deletion (Indel) mutations, the widespread structural variants (SVs) have been overlooked. SVs are pervasive in roughly 94.9% of tumors and possess the po