Introduction: A Plasma-Derived Marvel in Modern Medicine
Human Albumin has firmly established itself as one of the most valuable and reliable biotherapeutics in critical and supportive care. Extracted and purified from human plasma, Human Albumin Injection is much more than just a volume expander—it is a life-saving therapeutic agent that plays an essential role in fluid resuscitation, oncotic pressure maintenance, and transport of various endogenous substances in the blood.
1. What is Human Albumin?
Human Albumin is a sterile, purified preparation of serum albumin protein derived from pooled human plasma. It constitutes about 60% of the total protein content in plasma and plays a vital physiological role in maintaining oncotic pressure and transporting hormones, fatty acids, and drugs. In clinical use, it is available as an injectable solution in varying concentrations—commonly 5%, 20%, and 25%.
Unlike synthetic volume expanders, Human Albumin is biologically compatible and does not carry the same risk of anaphylaxis or coagulopathy, making it an ideal candidate in many critical care settings.
2. Composition and Formulations
Each vial of Human Albumin contains:
- Active Ingredient: Human Albumin (USP), typically 5 g, 20 g, or 25 g per 100 mL depending on concentration.
- Stabilizers: Sodium caprylate and sodium acetyltryptophanate to maintain stability and prevent aggregation.
- Sodium Content: Varies depending on concentration.
- pH Range: Generally maintained between 6.9 to 7.5.
Formulations are isotonic and heat-treated to inactivate potential viruses, ensuring high levels of safety and purity for patient use.
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